1From the outset, the team knew that the project would be a complex and time-consuming endeavour.
2The company's financial struggles from the outset made it difficult for it to secure funding for its new venture.
3At the outset of the negotiations, both parties agreed to maintain open communication and a willingness to compromise.
4The researchers were aware of the potential risks from the outset and took necessary precautions to ensure the safety of their participants.
5Despite the challenges that arose from the outset, the team persevered and ultimately achieved their goal.