1The company's decision to downsize will irrevocably alter the local economy.
2Was the damage to the ecosystem irrevocably done, or can it still be restored?
3Her actions will irrevocably damage her reputation if they become public knowledge.
4Try not to make any decisions that will irrevocably commit you to a particular course of action.
5The new policy will irrevocably change the way we approach customer service in our industry.