1She was an astute observer of human behavior and was able to pick up on subtle cues that others might miss.
2The company's astute financial manager was able to navigate the business through a difficult period of economic downturn.
3As an astute politician, he was able to build a coalition of supporters from across the party spectrum.
4The detective was astute enough to realize that the suspect was hiding something, and she was determined to find out what it was.
5The astute reader will notice that the author's use of language is not just decorative, but also serves to convey a deeper meaning.