1The news of her passing affected him profoundly, and he took months to recover from the loss.
2The team's victory was profoundly satisfying, especially given the difficult circumstances they had faced.
3The new policy has profoundly impacted the local community, leading to widespread protests and calls for reform.
4She was profoundly moved by the beauty of the art exhibition and felt inspired to create something of her own.
5The discovery of dark matter has profoundly changed our understanding of the universe and its many mysteries.