1The Black Death, a pandemic that ravaged Europe in the 14th century, is considered one of the deadliest plagues in human history.
2The recent outbreak of the virus has raised concerns about the potential for a plague of global proportions.
3The city's poor sanitation and lack of clean water have created a plague of waterborne diseases.
4The constant noise from the construction site has become a plague to the residents of the nearby apartments.
5Efforts to eradicate the plague of malaria have been hindered by the development of resistance to existing treatments.