1The malady that had afflicted her family for generations was finally understood and treated thanks to advances in genetic research.
2Is it possible to write a compelling novel about a character struggling with a debilitating malady without resorting to melodrama?
3The doctor's diagnosis revealed a complex malady that required a multifaceted treatment approach.
4Avoid using the term 'malady' in informal conversation; it may come across as overly formal or even pretentious.
5There is a long tradition of literary works exploring the human experience of living with a chronic malady, from the Romantic poets to modern memoirs.