1The constant noise from the construction site has been a major source of irritation for the residents of the building.
2She expressed her irritation at the lack of progress in the project, citing the need for more resources and better management.
3The new policy has been a cause of irritation for many employees, who feel that it unfairly restricts their freedom to make decisions.
4After a long and tiring day, the last thing he needed was the irritation of a traffic jam on his way home.
5The therapist helped her patient to identify and relieve the underlying irritation that was causing her anxiety and stress.